Original Research Article I Volume 3 I Issue 3 I 2017
A Novel Prolinamide Organo-Catalyst for the Asymmetric Aldol Reaction: Synthesis of ß- Hydroxyketones
Kanugula Bhavani, J. S. Yadav
The American Journal of Science and Medical Research; 3(4); 1-4
DOI:http://dx.doi.org/10.17812/ajsmr3401
Abstract:
A new L-prolinamide catalyst has been synthesized for the enantioselectivealdol reaction of various aldehydes with acetone. This method provides high yields of β-hydroxyketones (up to 90%) with good enantioselectivity (up to 90%) using a low catalyst loading (5 mol%)
Keywords:
Aldol reaction, benzo[d]oxazol-2-amine, proline, enantioselectivity.
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Article Dates:
Received: 21 November 2017 ; Accepted: 24 December, 2017 ; Published: 30 December 2017
How To Cite:
http://dx.doi.org/10.17812/ajsmr3401 Received :21 November, 2017 Accepted; 24 December, 2017 Available online : 30 December, 2017
