Original Research Article I Volume 2 I Issue 3 I 2016

Genetic and biochemical markers in Emphysema

G. Arumugam, A. Mohamed Sadiq, M. Nagalingam, A. Panneerselvam

American Journal of Science and Medical Research; 2(3); 193-199

DOI:http://dx.doi.org/10.17812/ajsmr127

Abstract:

Aim of the present study to evaluate the Chronic Obstructive Pulmonary Disease (COPD), also known as chronic obstructive airway disease (COAD), is a group of diseases characterized by the pathological limitation of airflow in the airway that is not fully reversible. Emphysema is a multifactorial disorder and involves interplay of genetic, inflammatory and oxidative factors during its progression. The study has the following objectives. To identify the polymorphic variants of TNF α and MMP3 with the disease. To understand the role of oxidants (Nitrate/Nitrite) and antioxidant (Ceruloplasmin) in the etiology of emphysema. To evaluate the role of the inflammatory marker (hs-CRP) in emphysema

Keywords:

Emphysema, Biochemical markers, PCR, Clinical studies, TNF α and MMP3 genes.

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Article Dates:

Received: 2 August 2016; Accepted: 11 September 2016; Published: 21 September 2016

How To Cite:

G. Arumugam, A. Mohamed Sadiq, M. Nagalingam, A. Panneerselvam (2016). Genetic and biochemical markers in Emphysema. The Ame J Sci & Med Res, 1(2):179-185.