Research Article I Volume 2 I Issue 2 I 2016
Epidemiological and Clinical Assessment of Influenza-Like Illness Patients at Gandhi Hospital from 2009 to 2012
Muttineni Radha Krishna, Trilok Chander Bingi
The American Journal of Science and Medical Research
DOI:DOI 10.5281/zenodo.14075433.
Abstract:
This study investigates the epidemiological and clinical characteristics of influenza-like illness (ILI) patients at Gandhi Hospital from 2009 to 2012, a period that included the H1N1 pandemic. A total of 1,239 patients were admitted with ILI symptoms, of whom 288 were confirmed as H1N1-positive, exhibiting a mortality rate of 10%. The majority of H1N1 cases occurred in individuals aged 30-45, with females comprising 60.1% of patients. Common symptoms included fever (98.2%) and cough (95.3%), while comorbid conditions, primarily COPD/asthma, were noted in 20.48% of cases. In contrast, non-H1N1 patients (951 cases) had a slightly higher mortality rate of 12%, with a greater prevalence of comorbidities (36.17%). The study utilized comprehensive assessments, including clinical, radiological, and laboratory evaluations, to compare outcomes and inform future public health strategies. Results underscore the need for effective management of ILI, particularly in high-risk groups, and highlight the impact of underlying health conditions on patient outcomes, emphasizing the importance of preparedness for future influenza outbreaks.
Keywords:
Influenza-like illness (ILI), H1N1 pandemic, Epidemiology, Mortality rate Comorbidities.
References:
[1] Klein, S. L., & Flanagan, K. L. (2016). Sex differences in immune responses. Nature Reviews Immunology, 16(10), 626-638.
[2] Jamieson DJ, Honein MA, Rasmussen SA, Williams JL, Swerdlow DL, Biggerstaff MS, Lindstrom S, Louie JK, Christ CM, Bohm SR, Fonseca VP, Ritger KA, Kuhles DJ, Eggers P, Bruce H, Davidson HA, Lutterloh E, Harris ML, Burke C, Cocoros N, Finelli L, MacFarlane KF, Shu B, Olsen SJ; Novel Influenza A (H1N1) Pregnancy Working Group. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet. 2009 Aug 8;374(9688):451-8.
[3] Rasmussen SA, Jamieson DJ, Macfarlane K, Cragan JD, Williams J, Henderson Z; Pandemic Influenza and Pregnancy Working Group. Pandemic influenza and pregnant women: summary of a meeting of experts. Am J Public Health. 2009 Oct;99 Suppl 2(Suppl 2):S248-54.Epub 2009 May 21.
[4] Vaillant, L., La Ruche, G., Tarantola, A., & Barboza, P. (2009). Epidemiology of fatal cases associated with pandemic H1N1 influenza 2009. Eurosurveillance, 14(33), 19309.
[5] Hsieh, YH. Age groups and spread of influenza: implications for vaccination strategy. BMC Infect Dis 10, 106 (2010).
[6] Mughini-Gras L, Pijnacker R, Enserink R, Heusinkveld M, van der Hoek W, van Pelt W. Influenza-like Illness in Households with Children of Preschool Age. Pediatr Infect Dis J. 2016 Mar;35(3):242-8.
[7] Minodier L, Charrel RN, Ceccaldi PE, van der Werf S, Blanchon T, Hanslik T, Falchi A. Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know? Virol J. 2015 Dec 12;12:215.
[8] O’Donnell, Denis E. and Pierantonio Laveneziana. “Physiology and consequences of lung hyperinflation in COPD.” European Respiratory Review 2006 15 (2006): 61 - 67.
[9] Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT Features of Viral Pneumonia. Radiographics. 2018 May-Jun;38(3):719-739.
[10] Thompson WW, Shay DK, Weintraub E, Brammer L, Cox N, Anderson LJ, Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA. 2003 Jan 8;289(2):179-86.
Wang R, Taubenberger JK. Methods for molecular surveillance of influenza. Expert
Article Dates:
Received 25 April, 2016; Accepted 29 May, 2016; Published online 25 June, 2016
How To Cite:
Muttineni Radha Krishna, Trilok Chander Bingi (2016). Epidemiological and Clinical Assessment of Influenza-Like Illness Patients at Gandhi Hospital from 2009 to 2012,2(2):179-182. Doi: 10.5281/zenodo.14075434 .